Profhilo Structura is the latest innovation from the creators of the original Profhilo – and it’s already transforming the world of injectable skin rejuvenation. As skin booster technology evolves, this next-generation treatment offers a more targeted, lifting, and firming effect for patients seeking natural, youthful results without the heaviness of traditional fillers.

What Is Profhilo Structura?
Profhilo Structura is an advanced hybrid hyaluronic acid formulation designed to restore structural integrity and firmness to ageing or lax skin. Building on the success of the original Profhilo, Structura is specifically engineered for deeper tissue remodeling – particularly in areas of volume loss such as the cheeks, jawline, and temples.
It combines two molecular weights of hyaluronic acid using NAHYCO® Hybrid Technology. The result? A highly stable hybrid complex that lasts longer in the skin, promotes collagen and elastin production, and improves tissue density from within.
Profhilo vs Profhilo Structura: What’s the Difference?
While both products share a foundation in bioremodeling, there are key differences in viscosity, target depth, and clinical effect.
- Profhilo: Primarily designed for superficial skin hydration, glow, and elasticity. Ideal for face, neck, and décolletage.
- Profhilo Structura: Formulated for deeper injection planes to support facial structure, improve firmness, and lift sagging areas.
In essence, Profhilo Structura acts as the bridge between a skin booster and a soft-tissue volumizer — firming without overfilling.

How Does Profhilo Structura Work?
When injected into the mid- to deep-dermal layers, Profhilo Structura stimulates fibroblasts and myofibroblasts to rebuild collagen and elastin. Its unique thermal bonding process allows slow release of hyaluronic acid, maintaining long-term hydration and structural remodeling without inflammation or swelling.
Benefits of Profhilo Structura
- Enhanced tissue support and firmness
- Natural lifting without volume distortion
- Improved elasticity and contour definition
- Minimized downtime and side effects
- Long-lasting structural improvement (up to 6–9 months)
Injection Technique and Treatment Areas
The recommended protocol for Profhilo Structura typically involves injection into the deep dermis or subcutaneous layer using either needle or cannula techniques. Target zones include:
- Midface (malar and submalar areas)
- Jawline and pre-jowl sulcus
- Temples
- Chin and mandibular angle
Due to its dense yet spreadable texture, Structura provides uniform distribution and integration into tissue, making it ideal for combination with other skin boosters or biostimulators.
Who Can Perform Profhilo Structura Treatments?
In the UK, Profhilo Structura is a medical injectable and can only be performed by qualified healthcare professionals such as doctors, dentists, nurses, and prescribing pharmacists who have received appropriate hands-on aesthetic training.
Practitioners should have advanced anatomical understanding and practical experience with skin boosters and injectable techniques before introducing Structura into their clinical practice.
How to Learn Profhilo Structura Injection Techniques
At Dr. Dray Academy, we teach the full spectrum of skin booster and PRP treatments, including advanced protocols like Profhilo and Profhilo Structura. Our CPD-accredited training focuses on:
- Anatomical injection mapping for skin boosters
- Safe needle and cannula techniques
- Combining Profhilo with PRP, polynucleotides, and exosomes
- Managing complications and achieving natural results
Our elite team — led by Dr. Maurice Dray and Dr. Michael Moore — has over 45 years of combined experience treating high-profile clients across London, Paris, and Abu Dhabi. You’ll gain exclusive insight into the methods trusted by celebrities and global leaders in aesthetic medicine.
Ready to Master Profhilo and Skin Booster Techniques?
Join our CPD-accredited Skin Booster & PRP Training Course at Dr. Dray Academy in London — or experience the complete in-person injectable mastery weekend.
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